The risk may be greater in people who have had these thoughts or actions in the past
It is designated 1,2,3,4,10,14b-hexahydro-2-methylpyrazino [2,1-a] pyrido [2,3-c] benzazepine and has the empirical formula of C 17 H 19 N 3
The enhancement of serotonergic neurotransmission is specifically mediated via 5-HT 1 receptors, because 5-HT 2 and 5-HT 3 receptors are blocked by mirtazapine
See contact details ATC code: N06AX11 About Medicine Prescription only medicine Healthcare Professionals (SmPC) Patient Leaflet (PIL) The Patient Information Leaflet (PIL) is the leaflet included in the pack with a medicine
Your doctor may adjust your dose if needed
These medicines work in the central nervous system (CNS) to make certain chemicals in the brain stronger
DESCRIPTION REMERON® (mirtazapine) Tablets are an orally administered drug
If any of these effects last or get worse Mirtazapine (Remeron, Remeron SolTab) is an oral medication used to treat depression
Dropouts occur similarly in participants treated with Mirtazapine is less likely than some other antidepressants to cause anticholinergic side effects such as dry mouth, constipation, urinary retention, bowel obstruction, dilated pupils, blurred vision, increased heart rate, and decreased sweating; however, it may still cause them
It should be taken preferably as a single night-time dose before going to bed
An internal pilot phase assessed trial recruitment, with progression Mirtazapine (MTZ) is an atypical antidepressant approved by the FDA, which mechanism of action involves the antagonism of alpha-2, H1, 5-HT2A, 5-HT2C, and 5-HT3 receptors
The effectiveness of mirtazapine is comparable to other commonly Mirtazapine (Remeron) is a first-choice antidepressant for the treatment of depression in adults
Loss of interest or pleasure in your usual activities
Call the doctor right away if signs like low mood (depression Patient and carer advice For mirtazapine
MIRTAZAPINE (mir TAZ a peen) treats depression
Mirtazapine may cause a serious condition called serotonin syndrome if taken together with some medicines
Keep using the medication as directed and tell your doctor if your symptoms do not improve after 4 weeks of treatment
This may be due to the way mirtazapine affects brain receptors for chemicals like serotonin and histamine
If you and your doctor decide to take you off mirtazapine, your doctor will probably recommend reducing your dose gradually to help prevent extra side effects
It's recommended that you take mirtazapine at bedtime to best manage this side effect
This leaflet should come with your medication Side Effects
Although not all of these side effects may occur, if they do occur they may need medical attention
Maintenance dose: 15 to 45 mg orally once a day
Medical experts believe mirtazapine works by balancing chemicals in the brain (such as serotonin and noradrenaline) that are thought to affect mood and emotions
Do not break, crush or chew them
It is at least as effective as the older antidepressants for treating mild to severe depression
Taking mirtazapine with other medicines and herbal supplements
Agranulocytosis: If sore throat, fever, stomatitis or signs of infection occur, along with a low white blood cell count, treatment with mirtazapine tablets should be discontinued and the patient should be closely monitored
It is slightly less popular than comparable drugs
Background: Mirtazapine is a commonly used antidepressant with a well-known ability to produce sedation
unusual tiredness or weakness
Low white blood cell count ( neutropenia) Postmarketing side effects of mirtazapine reported include: Severe skin reactions: Stevens-Johnson syndrome
Take this medication exactly as prescribed and discuss with your doctor before starting any other medication (prescribed or over the counter) while on mirtazapine, as adverse effects can occur
The 30 mg tablets are beige, film-coated, round, scored tablets debossed with M over 530 on one side of the However, if the side effects last longer than that, bother you, or become severe, be sure to talk with your doctor or pharmacist
Ask your GP or pharmacist for more information about off-label use
John's wort, or some pain or migraine medicines (eg, rizatriptan, sumatriptan, tramadol, Frova®, Imitrex®, Maxalt®, Relpax®, Ultram®, Zomig®)
Do not use mirtazapine with buspirone (Buspar®), fentanyl (Abstral®, Duragesic®), lithium (Eskalith®, Lithobid®), tryptophan, St
orthostasis, syncope), serotonin syndrome, severe Mirtazapine is used to treat depression
fluoxetine
6 Cases of suicidal ideation and suicidal behaviours have been reported during mirtazapine therapy or early after treatment discontinuation (see section 4
Call the doctor right away if signs like low mood (depression), nervousness, restlessness, grouchiness, panic attacks, or changes in mood or actions are new or worse
If weight gain is noticed while taking mirtazapine, get advice from your healthcare provider
About Medicine
ATC code: N06AX11
Active Ingredient
Remeron RD
Company: Aurobindo Pharma - Milpharm Ltd
Mirtazapine, is a moderate peripheral α 1-adrenergic
Mirtazapine is an antidepressant that doctors prescribe to treat depression
Zismirt 30 mg Film-Coated Tablets
Qi Wang, Meina Ma, Hong Yu, Hongmei Yu, Shuai Zhang & Rui Li
Along with its needed effects, mirtazapine may cause some unwanted effects
Mirtazapine is a tetracyclic piperazino-azepine antidepressant agent that was initially approved for the treatment of major depressive disorder (MDD) in the Netherlands in 1994
Common side effects of mirtazapine include drowsiness, increased appetite and weight gain
Mirtazapine also comes as tablets that melt in your mouth (orodispersible tablets)
Who can and cannot take it
• Serotonin Syndrome: Increased risk when co-administered with other serotonergic drugs (e
The purpose of this article is to provide clinicians with a detailed review of mirtazapine's sleep effects in patients with MDD
Other side effects of mirtazapine include: Worsening depression
It was first synthesized in The Netherlands in 1987 1 and introduced in the United States in 1996
racing thoughts, decreased need for sleep, unusual risk-taking behavior, feelings of extreme happiness or sadness, being more talkative than usual; blurred vision, tunnel vision, eye pain or 3
However, if the side effects last longer than that, bother you, or become severe, be sure to talk with your doctor or pharmacist
Atypical antidepressants are frequently used in patients with major depression who have inadequate responses or intolerable side effects during first-line treatment with SSRIs [ 2 ]
Heart rhythm problems (eg, QT prolongation) or
Mirtazapine belongs to a group of medicines called tetracyclic antidepressants
This likely permits greater activity of other, unblocked adrenergic and serotonin receptors and